Citrate transporter family protein
WebProtein family/group databases. TCDB. 2.A.29.7.1 the mitochondrial carrier (mc) family; Names & Taxonomy. Protein names ... Citrate carrier 1 publication (CIC 1 publication) … WebOct 29, 2024 · Summary. This gene encodes a member of the mitochondrial carrier family. The encoded protein is responsible for the movement of tricarboxylates, such as citrate, across the inner mitochondrial membrane. It is essential to the bioenergetics of hepatic cells, supplying the cytoplasm with a carbon source for fatty acid and sterol biosynthesis, and ...
Citrate transporter family protein
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WebSep 29, 2012 · The 2-oxoglutarate carrier (OGC) belongs to the mitochondrial carrier protein family whose members are responsible for the exchange of metabolites, cofactors and nucleotides between the cytoplasm and mitochondrial matrix. Initially, OGC was characterized by determining substrate specificity, kinetic parameters of transport, … WebJul 1, 2007 · The cellular transport of long-chain fatty acids (LCFAs) across the plasma membrane has long been thought to occur via passive diffusion. However, in recent years a substantial body of literature has emerged indicating that LCFA uptake into muscle cells occurs via a protein-mediated process (for review see Bonen et al. 2002; Luiken et al. …
WebJun 1, 2003 · Protein family/group databases. TCDB. 2.A.47.1.9 the divalent anion:na + symporter (dass) family; Names & Taxonomy. Protein names. ... Sodium-coupled citrate transporter 1 publication. Sodium-dependent citrate transporter; Solute carrier family 13 member 5; Gene names. Name. SLC13A5. Synonyms. NACT. Organism names. … WebJun 14, 2024 · Introduction. L-lactate is an important metabolite in health and disease 1. Its stereoselective transport across plasma membranes is mainly catalyzed by monocarboxylate transporters (MCTs) of the ...
WebAug 1, 2024 · The recently determined crystal structure of the bacterial Na +-citrate symporter CitS provides unexpected structural and mechanistic insights. The protein has a fold that has not been seen in other proteins, but the oligomeric state, domain organization and proposed transport mechanism strongly resemble those of the sodium … WebLiver cells import citrate through the sodium-dependent citrate transporter NaCT (encoded by SLC13A5) and, as a consequence, this protein is a potential target for anti-obesity …
WebFeb 23, 2024 · The small molecule citrate is a key molecule that is synthesized de novo and involved in diverse biochemical pathways influencing cell metabolism and function. Citrate is highly abundant in the circulation, and cells take up extracellular citrate via the sodium-dependent plasma membrane transporter NaCT encoded by the SLC13A5 gene. …
WebMay 14, 2024 · The citrate transport activity of the protein was studied in CT reconstituted liposomes. Our results showed high efficiency of CT for [ 14 C] citrate/citrate exchange with K m 0.01 mM at 25°C. easy hamburger goulash skillet recipeWebNational Center for Biotechnology Information curious adsWebSLC13A5. Solute carrier family 13 (sodium-dependent citrate transporter), member 5 also known as the Na+/citrate cotransporter or mIndy is a protein that in humans is encoded by the SLC13A5 gene. [5] It is the mammalian homolog of the fly Indy gene . curious about中文WebMar 1, 2024 · The Mitochondrial Carrier Family. With 53 members, the mitochondrial carrier family (solute carrier family 25, SLC25) is the largest solute transporter family in humans. They transport solutes across the impermeable inner membrane of mitochondria for important cellular processes, such as oxidative phosphorylation of fats and sugars, … curious about snow by gina shawWebFeb 11, 2002 · Citrate transport protein (CTP) Mitochondrial citrate carrier 1 publication (CIC 1 publication) Solute carrier family 25 member 1; Tricarboxylate carrier protein; … curious about glasgow science centreWebJan 20, 2024 · Moreover, mutations of a member of the citrate transporter family in fruit fly, INDY, promote longevity, ... Inhibitors of the mitochondrial citrate transport protein: validation of the role of ... curious and activeWebWe have characterized a nodule-specific citrate transporter of the multidrug and toxic compound extrusion family, MtMATE67 of Medicago truncatula The MtMATE67 gene was induced early during nodule development and expressed primarily in the invasion zone of mature nodules. The MtMATE67 protein was localized to the plasma membrane of … curious and active scripture