Imine hydroboration
WitrynaImine reduction is one of the most frequently used transformations in organic synthesis. In this work, we developed novel partially carbonized chitin/Ru microspheres … Witryna17 wrz 2024 · Catalytic hydroboration of imines is a simple and straight-forward method for the preparation of amines, unlike conventional hydrogenation reactions and …
Imine hydroboration
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Witrynacatalyst for imine hydroboration with pinacolborane at room temperature† Hanbi Kim, Hyun Tae Kim, Ji Hye Lee, Hyonseok Hwang and Duk Keun An * An efficient protocol … Witryna19 cze 2024 · The rarely used boron Lewis acid tris[3,5-bis(trifluoromethyl)phenyl]borane (BArF3) is found to be an excellent catalyst for metal-free hydroboration of imines. In …
WitrynaHydroboration of nitriles and imines mediated by main‐group metal Mg under solvent‐free conditions has been reported. Simple ethoxymagnesium chloride (EtOMgCl) was found to be an effective promoter of nitrile and imine hydroboration at room temperature. The selective reduction of nitriles over alkenes and alkynes and … WitrynaWe report the use of a cyclic carbodiphosphorane catalyst for ketone and imine hydroboration reactions. Ketone hydroboration reactions are particularly rapid, typically reaching completion within 15 min using a 1 mol % catalyst loading at 25 °C. To our knowledge, this represents the first use of a carbodiphosphorane as an …
Witryna27 lip 2024 · In summary, we have developed an approach for catalytic, mild and high-yielding hydroboration of nitriles. The catalyst system, consisting of a borane with comparably low Lewis acidity and a Lewis base, reacts with pinacolborane reversibly, providing a borenium cation for the imine activation while simultaneously generating a …
Witryna28 paź 2024 · @article{Jaladi2024LithiumDH, title={Lithium diisobutyl-tert-butoxyaluminum hydride (LDBBA) catalyzed hydroboration of alkynes and imines with pinacolborane}, author={Ashok Kumar Jaladi and Hanbi Kim and Ji Hye Lee and Won Kyu Shin and Hyonseok Hwang and Duk Keun An}, journal={New Journal of …
Witryna27 mar 2024 · Compound 1 catalyzed chemoselective reduction of esters in the presence of other reducible functional groups such as alkene, alkyne and nitro is shown. Magnesium amide complexes such as Mg{N(SiMe3)2}2 (1) xylLMgN(SiMe3)2·THF (2) [xylL = ArNC(NiPr2)NAr; (Ar = 2,6-Me2-C6H3)] and dippLMgN(SiMe3)2·THF (3) … orc 731.14Witryna27 mar 2024 · An overview of hydrogenation and hydroboration of amides is presented in the subsequent section. Finally, late-stage chemoselective functional group manipulation reduction is described, and we conclude the review with a summary of recent progress in catalytic metal-free reduction of amides. ... ester, ketone, … orc 72408Witryna16 wrz 2024 · Imine hydroboration has perennially featured in notable reports while nitrile and carbodiimide hydroboration have gained attention recently. Initial developments in catalytic hydroboration of ... orc 721.15Witryna13 lut 2024 · Amines also promote imine reduction in certain cases, raising the possibility of a slow autocatalytic reaction. The ability of water or other protic impurities to promote the reduction of imines with pinacolborane represents an important identification of a potential source of background reaction in catalyzed reductions of imines. ... orc 727Witryna23 lut 2024 · We describe a simple and efficient procedure for nucleophilic borylation of imines in the absence of a photoredox catalyst. Visible light irradiation of an … orc 733WitrynaThe catalytic dehydrocoupling of amine–boranes has recently received a great deal of attention due to its potential in hydrogen storage applications. The use of aluminum catalysts for this transformation would provide an additional cost-effective and sustainable approach towards the hydrogen economy. Herein, we report the use of … orc 729Witryna11 sty 2024 · Detailed DFT calculations and experiments were performed to study the hydroboration mechanisms of two different kinds of imines. Our results revealed that … ipratropium and trimbow