Rptecs是什么
WebROC的全名叫做Receiver Operating Characteristic,其主要分析工具是一个画在二维平面上的曲线——ROC 曲线。平面的横坐标是false positive rate(FPR),纵坐标是true positive rate(TPR)。对某个分类器而言,我们可以根据其在测试样本上的表现得到一个TPR和FPR点对。这样,此分类器就可以映射成ROC平面上的一个点。调整 ... WebHuman renal proximal tubule epithelial cells (RPTECs) are commonly used to predict human renal drug permeability and to investigate drug efflux. However, current methods for investigating drug-transporter interactions involve inhibitors or knockdown methods that …
Rptecs是什么
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WebProduct Overview. Lonza's Human Renal Cells include cells isolated from various normal human kidney tissue specific to each cell type. Human Renal Proximal Tubule Cells are … WebBackground: Glucotoxicity in renal tubular epithelial cells (RPTECs) contributes to the pathogenesis of diabetic nephropathy. Sodium-glucose cotransporter 2 (SGLT2) inhibitors may exert their renoprotective effect by preventing glucotoxicity. We tested whether the confirmed in capillary endothelial cells unifying model of glucotoxicity can be applied in …
WebMar 8, 2024 · rptecs是肾小管中最常见的上皮细胞,具有吸收、分泌和转运等重要生理功能,对维持体内水盐平衡和酸碱平衡、代谢产物的清除等起着重要作用。 此外,RPTECs还 … Web百度百科是一部内容开放、自由的网络百科全书,旨在创造一个涵盖所有领域知识,服务所有互联网用户的中文知识性百科全书。在这里你可以参与词条编辑,分享贡献你的知识。
WebJul 17, 2024 · RPTECs showed similar degrees of apoptosis and Yes-associated protein (YAP) nuclear localization regardless of stiffness, suggesting these were not key mediators of the effect. However, focal adhesion formation, cytoskeletal organization, focal adhesion kinase (FAK) activation, and extracellular signal-regulated kinase (ERK) activation were all ... WebE , qRT-PCR analysis for the abundance of circHIPK3, HIPK3 mRNA, and β-ACTIN mRNA in RPTECs treated with RNase R. The amounts of target RNAs were normalized to those in the mock treatment. F , the stability of circHIPK3 and HIPK3 mRNA in RPTECs. Cells were treated with 5 μM actinomycin D (ActD), and RNA was extracted at the indicated time …
WebPTE学术英语考试(英语:Pearson Test of English Academic,简称PTE Academic),亦译作培生学术英语考试。. 培生学术英语考试是由金融 … shoprite dolson middletown nyWebGliflozins are a new class of antidiabetic drugs with renoprotective properties. In cultures of primary human renal tubular epithelial cells (RPTECs) subjected to high-glucose conditions in the presence or absence of dapagliflozin, we evaluated cellular senescence pathways. High glucose increased sodium–glucose cotransporter-2 (SGLT-2) expression and … shoprite distribution centre port elizabethWebUnfortunately, primary renal epithelial cells lose OAT1, OCT2, and OAT3 transporter expression quickly in culture. By utilizing hTERT-immortalized primary renal proximal tubule epithelial cells (RPTECs), ATCC has been able to create kidney transporter cell models that stably overexpress either the OAT1, OCT2, or OAT3 gene, and maintain routine ... shoprite dog food priceWebSep 30, 2024 · During hibernation, repeated cycles of ischemia-reperfusion (I-R) leave vital organs without injury. Studying this phenomenon may reveal pathways applicable to improving outcomes in I-R injury-induced human diseases. We evaluated whether the H2S–nuclear factor erythroid 2-like 2 (Nrf2)–antioxidant proteins axis … shoprite donation formWebMay 13, 2024 · Understanding the unique susceptibility of the human kidney to pH dysfunction and injury in cystinosis is paramount to develop new therapies to preserve renal function. Renal proximal tubular epithelial cells (RPTECs) and fibroblasts, isolated from patients with cystinosis were transcriptionally profiled. Lysosomal fractionation, … shoprite dixwellWebRPTEC/TERT1人肾近端. 收藏. 价格 ¥1500. 产地 中国/进口. 货号 HTX2664C. 品牌 华拓生物. 技术资料 查看技术资料. 丁香通用户服务中心 查看详情. 在线咨询. shoprite divisional office centurionWebThe following protocol describes how to transfect plasmid DNA into primary RPTECs using the TransfeX Reagent in a single well of a 12 well plate. The reaction may be scaled up as needed. Please refer to Table 1 for recommended reaction conditions for other dish or plate sizes. A. Preparation of the cells for transfection The day before ... shoprite donations